substitution for "narrow therapeutic index" (NTI) drugs

    The new generic warfarin is raising a big controversy about substitution for "narrow therapeutic index" (NTI) drugs.

    It's true that some drugs have a narrow range between doses that are subpotent...and doses that are toxic. Warfarin is one.

    There are others...carbamazepine...digoxin...levothyroxine...phenytoin...theophylline.

Practical advice for a better career, with unlimited access to CE

Pharmacy Technician's Letter includes:

  • 12 issues every year, with brief articles about new meds and hot topics
  • 120+ CE courses, including the popular CE-in-the-Letter
  • Helpful, in-depth Technician Tutorials
  • Access to the entire archive

Already a subscriber? Log in

Volume pricing available. Get a quote