You should cut the dose of Glucovance in half when switching patients who are already taking glyburide and metformin separately.

Absolutely not. DON'T do it.

We can see how a rumor like this could have gotten started.

It is true that the amount of glyburide absorbed in a Glucovance tablet isn't equivalent to regular glyburide tabs. Glucovance provides slightly greater absorption, about 7% to 18% more glyburide is absorbed.

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