Acetaminophen can cause high blood pressure.
Observational studies suggest that frequent users of acetaminophen, NSAIDs, and aspirin are more likely to develop hypertension than non-users of these pain relievers.
It's well-known that NSAIDs can cause blood pressure to go up. But acetaminophen is a surprise.
Researchers say that it may be related to the inhibition of prostaglandins in the kidney.