new concerns about using Viagra (sildenafil) in patients taking HIV protease inhibitors

There are new concerns about using Viagra (sildenafil) in patients taking HIV protease inhibitors.

Protease inhibitors slow Viagra metabolism...leading to significantly higher and more prolonged levels.

Saquinavir (Invirase) can DOUBLE plasma levels of Viagra...ritonavir (Norvir) can cause a 4-fold increase.

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