Watch for Labeling Changes About Amputations With Invokana

You'll see a new boxed warning about an increased risk of amputations with the diabetes med, canagliflozin (Invokana, etc).

This is the latest in a growing list of "flozin" concerns...ketoacidosis, urinary tract infections, yeast infections, etc.

Amputations, mainly of the toe or mid-foot, are seen in about 6 in 1,000 patients taking canagliflozin per year...compared to about 3 in 1,000 patients per year on other diabetes meds.

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