Think of Ajovy and Emgality as Similar to Aimovig for Migraine Prophylaxis

Ajovy (uh-JOH-vee, fremanezumab) and Emgality (em-GAL-ih-tee, galcanezumab) will join Aimovig (erenumab) to PREVENT migraine in adults.

These injectable biologics decrease migraines by blocking calcitonin gene-related peptide (CGRP). They'll be saved for when oral meds to prevent migraine...such as propranolol or topiramate...aren't enough.

Watch for payer messaging with these "CGRP antagonists." They're likely to require prior auths and may be considered specialty meds...partly because they each cost about $6,900/year.