strategies for treatment-resistant depression
May 2006
New evidence will improve strategies for treatment-resistant depression. More than HALF of patients continue to have symptoms after initial treatment for depression.
Switching to a different antidepressant is helpful in about 25% of patients who don't respond to an SSRI.
A patient may not even need to switch to a different class. For example, patients who don't respond to citalopram are as likely to respond to sertraline as they are to venlafaxine or bupropion.
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