drug interaction alerts between methotrexate and "PPI" stomach acid reducers (omeprazole, pantoprazole, etc)

December 2012

You'll encounter drug interaction alerts between methotrexate and "PPI" stomach acid reducers (omeprazole, pantoprazole, etc).

PPIs can boost methotrexate levels...possibly leading to liver damage, immune system suppression, and death.

The higher the dose of methotrexate, the higher the risk of toxicity. But problems can still occur with lower doses.

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Table of Contents

Vaccines more focus on proper vaccine storage
Antidepressants The new Forfivo XL (for-FIVE-oh, bupropion) will increase the chance of mix-ups among bupropion forms
Rheumatoid Arthritis Rayos, a new delayed-release prednisone
Interactions drug interaction alerts between methotrexate and "PPI" stomach acid reducers (omeprazole, pantoprazole, etc)
Gastroenterology the new drug, Linzess (lin-ZESS, linaclotide)
Side Effects more about bleeding with Pradaxa (dabigatran) and Xarelto (rivaroxaban)
Beta-Blockers changes in prescriptions for "beta-blockers" (propranolol, metoprolol, etc) being used for heart disease
Inhalers Tudorza Pressair (TU-door-za, aclidinium), for chronic obstructive pulmonary disease (COPD)
Diabetes debate about whether diabetes patients who don't use insulin benefit from monitoring their blood sugar
Anticoagulants increase in Xarelto (rivaroxaban) prescriptions
Gout rev up promotion of Uloric for managing gout
Vaccines Prevnar 13 vaccine will be used in certain ADULTS
Compounding new oversight of pharmacy compounding
Practice enjoy the holiday letter from our staff