Alert Pharmacists of Interactions with TMP/SMX and BP Meds

January 2015

We're getting questions about handling drug interaction alerts for TMP/SMX (Bactrim DS, etc) with certain BP meds (enalapril, etc).

This interaction is more risky than previously thought...and is popping up on more pharmacy system drug interaction checkers.

Trimethoprim (TMP) can increase potassium blood levels.

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Table of Contents

Vaccines Stay Alert for Orders That Require Vaccines to be Mixed
Generics Feel Comfortable Substituting Actavis' Methylphenidate ER Tabs for Concerta
Practice Break Quality Measures Tasks Into Small Chunks and Divide Them Among Coworkers
Inhalers Watch for Mix-Ups Between Spiriva Respimat and Handihaler
Chemotherapy Apply a "Cytotoxic" Auxiliary Label to Oral Chemo Rxs
Eye Health Point Out Administration Instructions for Lubricant Eye Gels on Product Labeling
Pregnancy & Nursing Expect Pregnant Women to use Enoxaparin for At Least Three Months After a Clot
Interactions Alert Pharmacists of Interactions with TMP/SMX and BP Meds
Med Administration Be Aware Tipping the Head Forward can Make Pill Swallowing Easier
Cholesterol Check Pack Sizes When Selecting Vytorin Bottles From Your Shelves
Needles & Syringes Feel Comfortable Dispensing the Highest Gauge Insulin Syringe Needle Available
Bipolar Disorder Look for Patients Who are Late or Not Refilling Their Bipolar Meds