Report Suspected Loperamide Misuse to FDA's MedWatch Program

July 2016

Please see the January 2018 FDA notice concerning new packaging for loperamide designed to limit abuse.

Abuse of OTC loperamide (Imodium A-D, etc) is skyrocketing...and is being linked to abnormal heart rhythms and deaths.

Loperamide used to be Schedule V. But it went OTC in the 1980s...since its abuse potential was thought to be very low.

Fast-forward to 2016 and loperamide has earned the nickname "poor man's methadone." High doses of loperamide can lead to opioid-like effects...and it costs as little as $8 for 400 tablets.

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