Help Optimize Penicillin Prophylaxis for Sickle Cell Disease
December 2024
You may see some pediatric patients with sickle cell disease take penicillin for YEARS...to prevent severe pneumococcal infections.
About 100,000 patients in the US have sickle cell disease...where red blood cells are crescent- or sickle-shaped due to a genetic mutation. This can clog the spleen...and impair its ability to fight infection.
“Penicillin prophylaxis” is given to kids with severe sickle cell disease to reduce the risk of serious infection...and possibly death.
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