two new anti-epileptics

March 2000

You'll see two new anti-epileptics...Trileptal (oxcarbazepine, Novartis) and Keppra (levetiracetam, UCB Pharma).

Trileptal is structurally related to Tegretol (carbamazepine).

Trileptal and Tegretol have similar efficacy...but Trileptal is less likely to cause serious hematologic toxicity or severe skin reactions.

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Table of Contents

whether hormone replacement therapy increases the risk of breast cancer
Gastroenterology Lotronex (alosetron), a new drug for irritable bowel syndrome (IBS)
Pediatrics Augmentin is more effective than Zithromax for otitis media
Pediatrics The first oral solution that contains ONLY trimethoprim
Immunizations new 2-dose regimen for giving Recombivax HB (hepatitis B vaccine) to ADOLESCENTS
Immunizations more widespread use of varicella vaccine (Varivax)
Cardiology whether vitamin E reduces the risk of heart disease
Women's Health Ortho-Prefest, a new combo HRT regimen for postmenopausal women
Women's Health metformin for Polycystic Ovary Syndrome (PCOS)
Ophthalmology three new eye drops for itching due to allergic conjunctivitis
Infectious Diseases Levaquin (levofloxacin) for treating penicillin-resistant pneumococcal pneumonia
Infectious Diseases Sporanox (itraconazole) now comes in IV form
which calcium supplement to recommend for a particular patient
Antiepileptics two new anti-epileptics
drug interactions with St. John's wort